Neuronal response to radical stress

Neuronal hemoglobin affects dopaminergic cells' response to stress

Hemoglobin (Hb) is the major protein in erythrocytes and carries oxygen (O2) throughout the body. Recently, Hb has been found synthesized in atypical sites, including the brain. Hb is highly expressed in A9 dopaminergic (DA) neurons of the substantia nigra (SN), whose selective degeneration leads to Parkinson's disease (PD). Here we show that Hb confers DA cells' susceptibility to 1-methyl-4-ph...

Neuronal Responses to Physiological Stress

Physiological stress can be defined as any external or internal condition that challenges the homeostasis of a cell or an organism. It can be divided into three different aspects: environmental stress, intrinsic developmental stress, and aging. Throughout life all living organisms are challenged by changes in the environment. Fluctuations in oxygen levels, temperature, and redox state for examp...

Natural antisense transcripts regulate the neuronal stress response and excitability

Neurons regulate ionic fluxes across their plasma membrane to maintain their excitable properties under varying environmental conditions. However, the mechanisms that regulate ion channels abundance remain poorly understood. Here we show that pickpocket 29 (ppk29), a gene that encodes a Drosophila degenerin/epithelial sodium channel (DEG/ENaC), regulates neuronal excitability via a protein-inde...

Response of two soybean cultivars to moisture stress

Response of Badami-Zarand Pistachio Rootstock to Salinity Stress

Salinity is one of the most important problems that restrict cultivation of crops in arid and semi-arid regions. Pistachio (Pistacia vera L.) is one of the most important trees that grow in these restricts. In this greenhouse study, the effects of salinity on growth of pistachio rootstock Badami evaluated. Seedlings were grown in plastic bags containing perlite. Salinity was imposed, by adding ...